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A Comparison of Commonly Used Ear Tags on the Ear Damage of Sheep
- D S Edwards, A M Johnston, D U Pfeiffer
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- Journal:
- Animal Welfare / Volume 10 / Issue 2 / May 2001
- Published online by Cambridge University Press:
- 11 January 2023, pp. 141-151
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The damage caused by ear tags used for sheep identification was investigated in a two-part study. In Part I, ear tags classified as metal loop, golf-tee, single flex or lambtag were inserted into the ears of 62 ewes. The severity of ewe ear lesions was monitored until 20 weeks after ear tag insertion. In Part II, 351 lambs had tags classified as metal loop, plastic loop, golf-tee, double flex, single flap, lambtag and electronic, inserted in their ears. The behaviour of the lambs was observed for 30s after insertion of the ear tag. The severity of lamb ear lesions was monitored until 5 weeks after ear tag insertion. In both ewes and lambs there was a significantly greater risk of severe and persistent ear lesions following the use of metal loop tags as compared with the other types of ear tag (P < 0.001). The single flap tag was difficult to insert in a greater proportion of lambs (P < 0.001), and more lambs haemorrhaged (P < 0.001), vocalized (P = 0.002) and shook their heads (P = 0.004) with it, than with the other types of ear tags. All ear tags resulted in an inflammatory reaction and required correct positioning to minimize the severity of ear lesions.
Australian square kilometre array pathfinder: I. system description
- Part of
- A. W. Hotan, J. D. Bunton, A. P. Chippendale, M. Whiting, J. Tuthill, V. A. Moss, D. McConnell, S. W. Amy, M. T. Huynh, J. R. Allison, C. S. Anderson, K. W. Bannister, E. Bastholm, R. Beresford, D. C.-J. Bock, R. Bolton, J. M. Chapman, K. Chow, J. D. Collier, F. R. Cooray, T. J. Cornwell, P. J. Diamond, P. G. Edwards, I. J. Feain, T. M. O. Franzen, D. George, N. Gupta, G. A. Hampson, L. Harvey-Smith, D. B. Hayman, I. Heywood, C. Jacka, C. A. Jackson, S. Jackson, K. Jeganathan, S. Johnston, M. Kesteven, D. Kleiner, B. S. Koribalski, K. Lee-Waddell, E. Lenc, E. S. Lensson, S. Mackay, E. K. Mahony, N. M. McClure-Griffiths, R. McConigley, P. Mirtschin, A. K. Ng, R. P. Norris, S. E. Pearce, C. Phillips, M. A. Pilawa, W. Raja, J. E. Reynolds, P. Roberts, D. N. Roxby, E. M. Sadler, M. Shields, A. E. T. Schinckel, P. Serra, R. D. Shaw, T. Sweetnam, E. R. Troup, A. Tzioumis, M. A. Voronkov, T. Westmeier
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- Publications of the Astronomical Society of Australia / Volume 38 / 2021
- Published online by Cambridge University Press:
- 05 March 2021, e009
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In this paper, we describe the system design and capabilities of the Australian Square Kilometre Array Pathfinder (ASKAP) radio telescope at the conclusion of its construction project and commencement of science operations. ASKAP is one of the first radio telescopes to deploy phased array feed (PAF) technology on a large scale, giving it an instantaneous field of view that covers $31\,\textrm{deg}^{2}$ at $800\,\textrm{MHz}$. As a two-dimensional array of 36$\times$12 m antennas, with baselines ranging from 22 m to 6 km, ASKAP also has excellent snapshot imaging capability and 10 arcsec resolution. This, combined with 288 MHz of instantaneous bandwidth and a unique third axis of rotation on each antenna, gives ASKAP the capability to create high dynamic range images of large sky areas very quickly. It is an excellent telescope for surveys between 700 and $1800\,\textrm{MHz}$ and is expected to facilitate great advances in our understanding of galaxy formation, cosmology, and radio transients while opening new parameter space for discovery of the unknown.
A National Spinal Muscular Atrophy Registry for Real-World Evidence
- Victoria L. Hodgkinson, Maryam Oskoui, Joshua Lounsberry, Saïd M’Dahoma, Emily Butler, Craig Campbell, Alex MacKenzie, Hugh J. McMillan, Louise Simard, Jiri Vajsar, Bernard Brais, Kristine M. Chapman, Nicolas Chrestian, Meghan Crone, Peter Dobrowolski, Susan Dojeiji, James J. Dowling, Nicolas Dupré, Angela Genge, Hernan Gonorazky, Simona Hasal, Aaron Izenberg, Wendy Johnston, Edward Leung, Hanns Lochmüller, Jean K. Mah, Alier Marerro, Rami Massie, Laura McAdam, Anna McCormick, Michel Melanson, Michelle M. Mezei, Cam-Tu E. Nguyen, Colleen O’Connell, Erin K. O’Ferrall, Gerald Pfeffer, Cecile Phan, Stephanie Plamondon, Chantal Poulin, Xavier Rodrigue, Kerri L. Schellenberg, Kathy Selby, Jordan Sheriko, Christen Shoesmith, Garth Smith, Monique Taillon, Sean Taylor, Jodi Warman Chardon, Scott Worley, Lawrence Korngut
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- Canadian Journal of Neurological Sciences / Volume 47 / Issue 6 / November 2020
- Published online by Cambridge University Press:
- 04 June 2020, pp. 810-815
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Background:
Spinal muscular atrophy (SMA) is a devastating rare disease that affects individuals regardless of ethnicity, gender, and age. The first-approved disease-modifying therapy for SMA, nusinursen, was approved by Health Canada, as well as by American and European regulatory agencies following positive clinical trial outcomes. The trials were conducted in a narrow pediatric population defined by age, severity, and genotype. Broad approval of therapy necessitates close follow-up of potential rare adverse events and effectiveness in the larger real-world population.
Methods:The Canadian Neuromuscular Disease Registry (CNDR) undertook an iterative multi-stakeholder process to expand the existing SMA dataset to capture items relevant to patient outcomes in a post-marketing environment. The CNDR SMA expanded registry is a longitudinal, prospective, observational study of patients with SMA in Canada designed to evaluate the safety and effectiveness of novel therapies and provide practical information unattainable in trials.
Results:The consensus expanded dataset includes items that address therapy effectiveness and safety and is collected in a multicenter, prospective, observational study, including SMA patients regardless of therapeutic status. The expanded dataset is aligned with global datasets to facilitate collaboration. Additionally, consensus dataset development aimed to standardize appropriate outcome measures across the network and broader Canadian community. Prospective outcome studies, data use, and analyses are independent of the funding partner.
Conclusion:Prospective outcome data collected will provide results on safety and effectiveness in a post-therapy approval era. These data are essential to inform improvements in care and access to therapy for all SMA patients.
An ultra-wide bandwidth (704 to 4 032 MHz) receiver for the Parkes radio telescope
- George Hobbs, Richard N. Manchester, Alex Dunning, Andrew Jameson, Paul Roberts, Daniel George, J. A. Green, John Tuthill, Lawrence Toomey, Jane F. Kaczmarek, Stacy Mader, Malte Marquarding, Azeem Ahmed, Shaun W. Amy, Matthew Bailes, Ron Beresford, N. D. R. Bhat, Douglas C.-J. Bock, Michael Bourne, Mark Bowen, Michael Brothers, Andrew D. Cameron, Ettore Carretti, Nick Carter, Santy Castillo, Raji Chekkala, Wan Cheng, Yoon Chung, Daniel A. Craig, Shi Dai, Joanne Dawson, James Dempsey, Paul Doherty, Bin Dong, Philip Edwards, Tuohutinuer Ergesh, Xuyang Gao, JinLin Han, Douglas Hayman, Balthasar Indermuehle, Kanapathippillai Jeganathan, Simon Johnston, Henry Kanoniuk, Michael Kesteven, Michael Kramer, Mark Leach, Vince Mcintyre, Vanessa Moss, Stefan Osłowski, Chris Phillips, Nathan Pope, Brett Preisig, Daniel Price, Ken Reeves, Les Reilly, John Reynolds, Tim Robishaw, Peter Roush, Tim Ruckley, Elaine Sadler, John Sarkissian, Sean Severs, Ryan Shannon, Ken Smart, Malcolm Smith, Stephanie Smith, Charlotte Sobey, Lister Staveley-Smith, Anastasios Tzioumis, Willem van Straten, Nina Wang, Linqing Wen, Matthew Whiting
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- Publications of the Astronomical Society of Australia / Volume 37 / 2020
- Published online by Cambridge University Press:
- 08 April 2020, e012
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We describe an ultra-wide-bandwidth, low-frequency receiver recently installed on the Parkes radio telescope. The receiver system provides continuous frequency coverage from 704 to 4032 MHz. For much of the band ( ${\sim}60\%$ ), the system temperature is approximately 22 K and the receiver system remains in a linear regime even in the presence of strong mobile phone transmissions. We discuss the scientific and technical aspects of the new receiver, including its astronomical objectives, as well as the feed, receiver, digitiser, and signal processor design. We describe the pipeline routines that form the archive-ready data products and how those data files can be accessed from the archives. The system performance is quantified, including the system noise and linearity, beam shape, antenna efficiency, polarisation calibration, and timing stability.
Correlating Microstructure to in situ Micromechanical Behaviour and Toughening Strategies in Biological Materials
- Richard E Johnston, Ria L Mitchell, Cameron Pleydell-Pearce, Mark Coleman, Laura North, David LaBonte, Michelle Oyen, Rachel Board, Edward C Pope, Hari Arora, David Howells
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- Journal:
- Microscopy and Microanalysis / Volume 25 / Issue S2 / August 2019
- Published online by Cambridge University Press:
- 05 August 2019, pp. 372-373
- Print publication:
- August 2019
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The CORE service improvement programme for mental health crisis resolution teams: results from a cluster-randomised trial
- Brynmor Lloyd-Evans, David Osborn, Louise Marston, Danielle Lamb, Gareth Ambler, Rachael Hunter, Oliver Mason, Sarah Sullivan, Claire Henderson, Steve Onyett, Elaine Johnston, Nicola Morant, Fiona Nolan, Kathleen Kelly, Marina Christoforou, Kate Fullarton, Rebecca Forsyth, Mike Davidson, Jonathan Piotrowski, Edward Mundy, Gary Bond, Sonia Johnson
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- Journal:
- The British Journal of Psychiatry / Volume 216 / Issue 6 / June 2020
- Published online by Cambridge University Press:
- 14 February 2019, pp. 314-322
- Print publication:
- June 2020
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Background
Crisis resolution teams (CRTs) offer brief, intensive home treatment for people experiencing mental health crisis. CRT implementation is highly variable; positive trial outcomes have not been reproduced in scaled-up CRT care.
AimsTo evaluate a 1-year programme to improve CRTs’ model fidelity in a non-masked, cluster-randomised trial (part of the Crisis team Optimisation and RElapse prevention (CORE) research programme, trial registration number: ISRCTN47185233).
MethodFifteen CRTs in England received an intervention, informed by the US Implementing Evidence-Based Practice project, involving support from a CRT facilitator, online implementation resources and regular team fidelity reviews. Ten control CRTs received no additional support. The primary outcome was patient satisfaction, measured by the Client Satisfaction Questionnaire (CSQ-8), completed by 15 patients per team at CRT discharge (n = 375). Secondary outcomes: CRT model fidelity, continuity of care, staff well-being, in-patient admissions and bed use and CRT readmissions were also evaluated.
ResultsAll CRTs were retained in the trial. Median follow-up CSQ-8 score was 28 in each group: the adjusted average in the intervention group was higher than in the control group by 0.97 (95% CI −1.02 to 2.97) but this was not significant (P = 0.34). There were fewer in-patient admissions, lower in-patient bed use and better staff psychological health in intervention teams. Model fidelity rose in most intervention teams and was significantly higher than in control teams at follow-up. There were no significant effects for other outcomes.
ConclusionsThe CRT service improvement programme did not achieve its primary aim of improving patient satisfaction. It showed some promise in improving CRT model fidelity and reducing acute in-patient admissions.
The Taipan Galaxy Survey: Scientific Goals and Observing Strategy
- Elisabete da Cunha, Andrew M. Hopkins, Matthew Colless, Edward N. Taylor, Chris Blake, Cullan Howlett, Christina Magoulas, John R. Lucey, Claudia Lagos, Kyler Kuehn, Yjan Gordon, Dilyar Barat, Fuyan Bian, Christian Wolf, Michael J. Cowley, Marc White, Ixandra Achitouv, Maciej Bilicki, Joss Bland-Hawthorn, Krzysztof Bolejko, Michael J. I. Brown, Rebecca Brown, Julia Bryant, Scott Croom, Tamara M. Davis, Simon P. Driver, Miroslav D. Filipovic, Samuel R. Hinton, Melanie Johnston-Hollitt, D. Heath Jones, Bärbel Koribalski, Dane Kleiner, Jon Lawrence, Nuria Lorente, Jeremy Mould, Matt S. Owers, Kevin Pimbblet, C. G. Tinney, Nicholas F. H. Tothill, Fred Watson
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- Publications of the Astronomical Society of Australia / Volume 34 / 2017
- Published online by Cambridge University Press:
- 24 October 2017, e047
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The Taipan galaxy survey (hereafter simply ‘Taipan’) is a multi-object spectroscopic survey starting in 2017 that will cover 2π steradians over the southern sky (δ ≲ 10°, |b| ≳ 10°), and obtain optical spectra for about two million galaxies out to z < 0.4. Taipan will use the newly refurbished 1.2-m UK Schmidt Telescope at Siding Spring Observatory with the new TAIPAN instrument, which includes an innovative ‘Starbugs’ positioning system capable of rapidly and simultaneously deploying up to 150 spectroscopic fibres (and up to 300 with a proposed upgrade) over the 6° diameter focal plane, and a purpose-built spectrograph operating in the range from 370 to 870 nm with resolving power R ≳ 2000. The main scientific goals of Taipan are (i) to measure the distance scale of the Universe (primarily governed by the local expansion rate, H0) to 1% precision, and the growth rate of structure to 5%; (ii) to make the most extensive map yet constructed of the total mass distribution and motions in the local Universe, using peculiar velocities based on improved Fundamental Plane distances, which will enable sensitive tests of gravitational physics; and (iii) to deliver a legacy sample of low-redshift galaxies as a unique laboratory for studying galaxy evolution as a function of dark matter halo and stellar mass and environment. The final survey, which will be completed within 5 yrs, will consist of a complete magnitude-limited sample (i ⩽ 17) of about 1.2 × 106 galaxies supplemented by an extension to higher redshifts and fainter magnitudes (i ⩽ 18.1) of a luminous red galaxy sample of about 0.8 × 106 galaxies. Observations and data processing will be carried out remotely and in a fully automated way, using a purpose-built automated ‘virtual observer’ software and an automated data reduction pipeline. The Taipan survey is deliberately designed to maximise its legacy value by complementing and enhancing current and planned surveys of the southern sky at wavelengths from the optical to the radio; it will become the primary redshift and optical spectroscopic reference catalogue for the local extragalactic Universe in the southern sky for the coming decade.
Promoting children's learning and development in conflict-affected countries: Testing change process in the Democratic Republic of the Congo
- J. Lawrence Aber, Carly Tubbs, Catalina Torrente, Peter F. Halpin, Brian Johnston, Leighann Starkey, Anjuli Shivshanker, Jeannie Annan, Edward Seidman, Sharon Wolf
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- Development and Psychopathology / Volume 29 / Issue 1 / February 2017
- Published online by Cambridge University Press:
- 21 November 2016, pp. 53-67
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Improving children's learning and development in conflict-affected countries is critically important for breaking the intergenerational transmission of violence and poverty. Yet there is currently a stunning lack of rigorous evidence as to whether and how programs to improve learning and development in conflict-affected countries actually work to bolster children's academic learning and socioemotional development. This study tests a theory of change derived from the fields of developmental psychopathology and social ecology about how a school-based universal socioemotional learning program, the International Rescue Committee's Learning to Read in a Healing Classroom (LRHC), impacts children's learning and development. The study was implemented in three conflict-affected provinces of the Democratic Republic of the Congo and employed a cluster-randomized waitlist control design to estimate impact. Using multilevel structural equation modeling techniques, we found support for the central pathways in the LRHC theory of change. Specifically, we found that LRHC differentially impacted dimensions of the quality of the school and classroom environment at the end of the first year of the intervention, and that in turn these dimensions of quality were differentially associated with child academic and socioemotional outcomes. Future implications and directions are discussed.
6 - Obstetrics for the anaesthetist
- from Section 2 - Obstetric aspects
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- By Emma Ingram, Academic Health Science Centre, Manchester, UK, Alex Heazell, Senior Clinical Lecturer and Honorary Consultant in Obstetrics, St Mary's Hospital, Manchester, UK, Edward D. Johnstone, Senior Clinical Lecturer, St Mary's Hospital and Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
- Edited by Kirsty MacLennan, Kate O'Brien, W. Ross Macnab
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- Core Topics in Obstetric Anaesthesia
- Published online:
- 05 December 2015
- Print publication:
- 26 October 2015, pp 35-43
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Summary
Intrapartum care at or near term gestation
Intrapartum care is a challenging and rapidly changing environment for all health professionals. As an obstetrician the key question is often ‘Do I need to intervene? And if so, how much time do I have to do this?’ Fetal monitoring, recommendation of mode and timing of delivery is aimed at reducing poor neonatal outcomes.
Within the scope of this chapter it is not possible to cover all potential intrapartum events that may require anaesthetic assessment and input. The aim of this chapter is to provide enough information on fetal monitoring to enable the anaesthetist to understand the urgency of a delivery and how this is determined in high-risk cases such as twins and vaginal breech delivery.
Intrapartum fetal monitoring
Intrapartum fetal monitoring techniques have enabled obstetricians to intervene and prevent the development of a severe hypoxia. However, these techniques are far from perfect. The mainstay of fetal intrapartum monitoring remains the cardiotocograph (CTG), which records the fetal heart rate (FHR) and the presence of uterine contraction activity using the tocograph. This is recommended by NICE for all ‘high-risk’ labours. Although not exhaustive, indications for continuous intrapartum CTG monitoring are listed below:
• Meconium-stained liquor
• Abnormal FHR detected by intermittent auscultation
• Maternal pyrexia of 38 °C on one occasion or 37.5°C on two occasions, 2 hours apart
• Fresh bleeding developing in labour
• Oxytocin use for augmentation
• Multiple pregnancy
• Vaginal breech delivery
• Maternal request
• Fetal growth restriction
• Preterm labour
• Maternal disease (pre-eclampsia, obstetric cholestasis).
The evidence for these recommendations is derived from observational studies rather than randomized controlled trials. The poor quality of these studies, which were performed more than 20 years ago, has resulted in a lack of evidence for CTG use in low-risk women. Therefore although it might seem counterintuitive to the anaesthetist to reduce the amount of monitoring information available to doctors and midwives caring for women in labour, current NICE guidance does not support the use of CTG in this group. A Cochrane review on continuous CTG during labour demonstrated a reduction in neonatal seizures, but no significant differences in cerebral palsy or infant mortality rates. This was offset by increases in caesarean section and instrumental vaginal birth rates.
Inclusion Body Myositis Masquerading as Amyotrophic Lateral Sclerosis
- Kerri L. Schellenberg, Wendy S. W. Johnston, Sanjay Kalra, Lothar Resch, Edward S. Johnson
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- Canadian Journal of Neurological Sciences / Volume 37 / Issue 5 / September 2010
- Published online by Cambridge University Press:
- 02 December 2014, pp. 687-691
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The Murchison Widefield Array Commissioning Survey: A Low-Frequency Catalogue of 14 110 Compact Radio Sources over 6 100 Square Degrees
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- Natasha Hurley-Walker, John Morgan, Randall B. Wayth, Paul J. Hancock, Martin E. Bell, Gianni Bernardi, Ramesh Bhat, Frank Briggs, Avinash A. Deshpande, Aaron Ewall-Wice, Lu Feng, Bryna J. Hazelton, Luke Hindson, Daniel C. Jacobs, David L. Kaplan, Nadia Kudryavtseva, Emil Lenc, Benjamin McKinley, Daniel Mitchell, Bart Pindor, Pietro Procopio, Divya Oberoi, André Offringa, Stephen Ord, Jennifer Riding, Judd D. Bowman, Roger Cappallo, Brian Corey, David Emrich, B. M. Gaensler, Robert Goeke, Lincoln Greenhill, Jacqueline Hewitt, Melanie Johnston-Hollitt, Justin Kasper, Eric Kratzenberg, Colin Lonsdale, Mervyn Lynch, Russell McWhirter, Miguel F. Morales, Edward Morgan, Thiagaraj Prabu, Alan Rogers, Anish Roshi, Udaya Shankar, K. Srivani, Ravi Subrahmanyan, Steven Tingay, Mark Waterson, Rachel Webster, Alan Whitney, Andrew Williams, Chris Williams
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- Journal:
- Publications of the Astronomical Society of Australia / Volume 31 / 2014
- Published online by Cambridge University Press:
- 14 November 2014, e045
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We present the results of an approximately 6 100 deg2 104–196 MHz radio sky survey performed with the Murchison Widefield Array during instrument commissioning between 2012 September and 2012 December: the MWACS. The data were taken as meridian drift scans with two different 32-antenna sub-arrays that were available during the commissioning period. The survey covers approximately 20.5 h < RA < 8.5 h, − 58° < Dec < −14°over three frequency bands centred on 119, 150 and 180 MHz, with image resolutions of 6–3 arcmin. The catalogue has 3 arcmin angular resolution and a typical noise level of 40 mJy beam− 1, with reduced sensitivity near the field boundaries and bright sources. We describe the data reduction strategy, based upon mosaicked snapshots, flux density calibration, and source-finding method. We present a catalogue of flux density and spectral index measurements for 14 110 sources, extracted from the mosaic, 1 247 of which are sub-components of complexes of sources.
The Australian Square Kilometre Array Pathfinder: System Architecture and Specifications of the Boolardy Engineering Test Array
- A. W. Hotan, J. D. Bunton, L. Harvey-Smith, B. Humphreys, B. D. Jeffs, T. Shimwell, J. Tuthill, M. Voronkov, G. Allen, S. Amy, K. Ardern, P. Axtens, L. Ball, K. Bannister, S. Barker, T. Bateman, R. Beresford, D. Bock, R. Bolton, M. Bowen, B. Boyle, R. Braun, S. Broadhurst, D. Brodrick, K. Brooks, M. Brothers, A. Brown, C. Cantrall, G. Carrad, J. Chapman, W. Cheng, A. Chippendale, Y. Chung, F. Cooray, T. Cornwell, E. Davis, L. de Souza, D. DeBoer, P. Diamond, P. Edwards, R. Ekers, I. Feain, D. Ferris, R. Forsyth, R. Gough, A. Grancea, N. Gupta, J. C. Guzman, G. Hampson, C. Haskins, S. Hay, D. Hayman, S. Hoyle, C. Jacka, C. Jackson, S. Jackson, K. Jeganathan, S. Johnston, J. Joseph, R. Kendall, M. Kesteven, D. Kiraly, B. Koribalski, M. Leach, E. Lenc, E. Lensson, L. Li, S. Mackay, A. Macleod, T. Maher, M. Marquarding, N. McClure-Griffiths, D. McConnell, S. Mickle, P. Mirtschin, R. Norris, S. Neuhold, A. Ng, J. O’Sullivan, J. Pathikulangara, S. Pearce, C. Phillips, R. Y. Qiao, J. E. Reynolds, A. Rispler, P. Roberts, D. Roxby, A. Schinckel, R. Shaw, M. Shields, M. Storey, T. Sweetnam, E. Troup, B. Turner, A. Tzioumis, T. Westmeier, M. Whiting, C. Wilson, T. Wilson, K. Wormnes, X. Wu
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- Publications of the Astronomical Society of Australia / Volume 31 / 2014
- Published online by Cambridge University Press:
- 13 November 2014, e041
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This paper describes the system architecture of a newly constructed radio telescope – the Boolardy engineering test array, which is a prototype of the Australian square kilometre array pathfinder telescope. Phased array feed technology is used to form multiple simultaneous beams per antenna, providing astronomers with unprecedented survey speed. The test array described here is a six-antenna interferometer, fitted with prototype signal processing hardware capable of forming at least nine dual-polarisation beams simultaneously, allowing several square degrees to be imaged in a single pointed observation. The main purpose of the test array is to develop beamforming and wide-field calibration methods for use with the full telescope, but it will also be capable of limited early science demonstrations.
Convectively driven shear and decreased heat flux
- David Goluskin, Hans Johnston, Glenn R. Flierl, Edward A. Spiegel
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- Journal of Fluid Mechanics / Volume 759 / 25 November 2014
- Published online by Cambridge University Press:
- 31 October 2014, pp. 360-385
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We report on direct numerical simulations of two-dimensional, horizontally periodic Rayleigh–Bénard convection between free-slip boundaries. We focus on the ability of the convection to drive large-scale horizontal flow that is vertically sheared. For the Prandtl numbers ($\mathit{Pr}$) between 1 and 10 simulated here, this large-scale shear can be induced by raising the Rayleigh number ($\mathit{Ra}$) sufficiently, and we explore the resulting convection for $\mathit{Ra}$ up to $10^{10}$. When present in our simulations, the sheared mean flow accounts for a large fraction of the total kinetic energy, and this fraction tends towards unity as $\mathit{Ra}\rightarrow \infty$. The shear helps disperse convective structures, and it reduces vertical heat flux; in parameter regimes where one state with large-scale shear and one without are both stable, the Nusselt number of the state with shear is smaller and grows more slowly with $\mathit{Ra}$. When the large-scale shear is present with $\mathit{Pr}\lesssim 2$, the convection undergoes strong global oscillations on long timescales, and heat transport occurs in bursts. Nusselt numbers, time-averaged over these bursts, vary non-monotonically with $\mathit{Ra}$ for $\mathit{Pr}=1$. When the shear is present with $\mathit{Pr}\gtrsim 3$, the flow does not burst, and convective heat transport is sustained at all times. Nusselt numbers then grow roughly as powers of $\mathit{Ra}$, but the growth rates are slower than any previously reported for Rayleigh–Bénard convection without large-scale shear. We find that the Nusselt numbers grow proportionally to $\mathit{Ra}^{0.077}$ when $\mathit{Pr}=3$ and to $\mathit{Ra}^{0.19}$ when $\mathit{Pr}=10$. Analogies with tokamak plasmas are described.
Contributors
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- By Victoria M. Allen, Frederic Amant, Sarah Armstrong, Thomas F. Baskett, Michael A. Belfort, Meredith Birsner, Renee D. Boss, Leanne Bricker, Josaphat K. Byamugisha, Giorgio Capogna, Michael P. Casaer, Frank A. Chervenak, Vicki Clark, Filip Claus, Malachy O. Columb, Charles Cox, Jean T. Cox, Vegard Dahl, John Davison, Jan Deprest, Clifford S. Deutschman, Roland Devlieger, Karim Djekidel, Steven Dymarkowski, Roshan Fernando, Clare Fitzpatrick, Sreedhar Gaddipati, Thierry Girard, Emily Gordon, Ian A. Greer, David Grooms, Sina Haeri, Katy Harrison, Edward J. Hayes, Michelle Hladunewich, Andra H. James, Tracey Johnston, Bellal Joseph, Erin Keely, Ruth Landau, Stephen E. Lapinsky, Susanna I. Lee, Larry Leeman, Hennie Lombaard, Stephen Lu, Alison MacArthur, Laura A. Magee, Paul E. Marik, Laurence B. McCullough, Alexandre Mignon, Carlo Missant, Jack Moodley, Lisa E. Moore, Kate Morse, Warwick D. Ngan Kee, Catherine Nelson-Piercy, Clemens M. Ortner, Geraldine O’Sullivan, Luis D. Pacheco, Fathima Paruk, Melina Pectasides, Nigel Pereira, Patricia Peticca, Sharon T. Phelan, Felicity Plaat, Lauren A. Plante, Michael P. Plevyak, Dianne Plews, Wendy Pollock, Laura C. Price, Peter Rhee, Leiv Arne Rosseland, Kathryn M. Rowan, Helen Ryan, Helen Scholefield, Neil S. Seligman, Nadir Sharawi, Alex Sia, Bob Silver, Mieke Soens, Ulrich J. Spreng, Silvia Stirparo, Nova Szoka, Andrew Tang, Kha M. Tran, Els Troost, Lawrence C. Tsen, Derek Tuffnell, Kristel Van Calsteren, Marc Van de Velde, Marcel Vercauteren, Chris Verslype, Peter von Dadelszen, Carl Waldman, Michelle Walters, Linda Watkins, Paul Westhead, Cynthia A. Wong, Gerda G. Zeeman, Joost J. Zwart
- Edited by Marc van de Velde, Helen Scholefield, Lauren A. Plante
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- Maternal Critical Care
- Published online:
- 05 July 2013
- Print publication:
- 04 July 2013, pp ix-xiv
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Science with the Murchison Widefield Array
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- Judd D. Bowman, Iver Cairns, David L. Kaplan, Tara Murphy, Divya Oberoi, Lister Staveley-Smith, Wayne Arcus, David G. Barnes, Gianni Bernardi, Frank H. Briggs, Shea Brown, John D. Bunton, Adam J. Burgasser, Roger J. Cappallo, Shami Chatterjee, Brian E. Corey, Anthea Coster, Avinash Deshpande, Ludi deSouza, David Emrich, Philip Erickson, Robert F. Goeke, B. M. Gaensler, Lincoln J. Greenhill, Lisa Harvey-Smith, Bryna J. Hazelton, David Herne, Jacqueline N. Hewitt, Melanie Johnston-Hollitt, Justin C. Kasper, Barton B. Kincaid, Ronald Koenig, Eric Kratzenberg, Colin J. Lonsdale, Mervyn J. Lynch, Lynn D. Matthews, S. Russell McWhirter, Daniel A. Mitchell, Miguel F. Morales, Edward H. Morgan, Stephen M. Ord, Joseph Pathikulangara, Thiagaraj Prabu, Ronald A. Remillard, Timothy Robishaw, Alan E. E. Rogers, Anish A. Roshi, Joseph E. Salah, Robert J. Sault, N. Udaya Shankar, K. S. Srivani, Jamie B. Stevens, Ravi Subrahmanyan, Steven J. Tingay, Randall B. Wayth, Mark Waterson, Rachel L. Webster, Alan R. Whitney, Andrew J. Williams, Christopher L. Williams, J. Stuart B. Wyithe
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- Journal:
- Publications of the Astronomical Society of Australia / Volume 30 / 2013
- Published online by Cambridge University Press:
- 16 April 2013, e031
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Significant new opportunities for astrophysics and cosmology have been identified at low radio frequencies. The Murchison Widefield Array is the first telescope in the southern hemisphere designed specifically to explore the low-frequency astronomical sky between 80 and 300 MHz with arcminute angular resolution and high survey efficiency. The telescope will enable new advances along four key science themes, including searching for redshifted 21-cm emission from the EoR in the early Universe; Galactic and extragalactic all-sky southern hemisphere surveys; time-domain astrophysics; and solar, heliospheric, and ionospheric science and space weather. The Murchison Widefield Array is located in Western Australia at the site of the planned Square Kilometre Array (SKA) low-band telescope and is the only low-frequency SKA precursor facility. In this paper, we review the performance properties of the Murchison Widefield Array and describe its primary scientific objectives.
Science with the Australian Square Kilometre Array Pathfinder
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- S. Johnston, M. Bailes, N. Bartel, C. Baugh, M. Bietenholz, C. Blake, R. Braun, J. Brown, S. Chatterjee, J. Darling, A. Deller, R. Dodson, P. G. Edwards, R. Ekers, S. Ellingsen, I. Feain, B. M. Gaensler, M. Haverkorn, G. Hobbs, A. Hopkins, C. Jackson, C. James, G. Joncas, V. Kaspi, V. Kilborn, B. Koribalski, R. Kothes, T. L. Landecker, E. Lenc, J. Lovell, J.-P. Macquart, R. Manchester, D. Matthews, N. M. McClure-Griffiths, R. Norris, U.-L. Pen, C. Phillips, C. Power, R. Protheroe, E. Sadler, B. Schmidt, I. Stairs, L. Staveley-Smith, J. Stil, R. Taylor, S. Tingay, A. Tzioumis, M. Walker, J. Wall, M. Wolleben
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- Publications of the Astronomical Society of Australia / Volume 24 / Issue 4 / 2007
- Published online by Cambridge University Press:
- 05 March 2013, pp. 174-188
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The future of centimetre and metre-wave astronomy lies with the Square Kilometre Array (SKA), a telescope under development by a consortium of 17 countries that will be 50 times more sensitive than any existing radio facility. Most of the key science for the SKA will be addressed through large-area imaging of the Universe at frequencies from a few hundred MHz to a few GHz. The Australian SKA Pathfinder (ASKAP) is a technology demonstrator aimed in the mid-frequency range, and achieves instantaneous wide-area imaging through the development and deployment of phased-array feed systems on parabolic reflectors. The large field-of-view makes ASKAP an unprecedented synoptic telescope that will make substantial advances in SKA key science. ASKAP will be located at the Murchison Radio Observatory in inland Western Australia, one of the most radio-quiet locations on the Earth and one of two sites selected by the international community as a potential location for the SKA. In this paper, we outline an ambitious science program for ASKAP, examining key science such as understanding the evolution, formation and population of galaxies including our own, understanding the magnetic Universe, revealing the transient radio sky and searching for gravitational waves.
Contributors
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- By Rose Teteki Abbey, K. C. Abraham, David Tuesday Adamo, LeRoy H. Aden, Efrain Agosto, Victor Aguilan, Gillian T. W. Ahlgren, Charanjit Kaur AjitSingh, Dorothy B E A Akoto, Giuseppe Alberigo, Daniel E. Albrecht, Ruth Albrecht, Daniel O. Aleshire, Urs Altermatt, Anand Amaladass, Michael Amaladoss, James N. Amanze, Lesley G. Anderson, Thomas C. Anderson, Victor Anderson, Hope S. Antone, María Pilar Aquino, Paula Arai, Victorio Araya Guillén, S. Wesley Ariarajah, Ellen T. Armour, Brett Gregory Armstrong, Atsuhiro Asano, Naim Stifan Ateek, Mahmoud Ayoub, John Alembillah Azumah, Mercedes L. García Bachmann, Irena Backus, J. Wayne Baker, Mieke Bal, Lewis V. Baldwin, William Barbieri, António Barbosa da Silva, David Basinger, Bolaji Olukemi Bateye, Oswald Bayer, Daniel H. Bays, Rosalie Beck, Nancy Elizabeth Bedford, Guy-Thomas Bedouelle, Chorbishop Seely Beggiani, Wolfgang Behringer, Christopher M. Bellitto, Byard Bennett, Harold V. Bennett, Teresa Berger, Miguel A. Bernad, Henley Bernard, Alan E. Bernstein, Jon L. Berquist, Johannes Beutler, Ana María Bidegain, Matthew P. Binkewicz, Jennifer Bird, Joseph Blenkinsopp, Dmytro Bondarenko, Paulo Bonfatti, Riet en Pim Bons-Storm, Jessica A. Boon, Marcus J. Borg, Mark Bosco, Peter C. Bouteneff, François Bovon, William D. Bowman, Paul S. Boyer, David Brakke, Richard E. Brantley, Marcus Braybrooke, Ian Breward, Ênio José da Costa Brito, Jewel Spears Brooker, Johannes Brosseder, Nicholas Canfield Read Brown, Robert F. Brown, Pamela K. Brubaker, Walter Brueggemann, Bishop Colin O. Buchanan, Stanley M. Burgess, Amy Nelson Burnett, J. Patout Burns, David B. Burrell, David Buttrick, James P. Byrd, Lavinia Byrne, Gerado Caetano, Marcos Caldas, Alkiviadis Calivas, William J. Callahan, Salvatore Calomino, Euan K. Cameron, William S. Campbell, Marcelo Ayres Camurça, Daniel F. Caner, Paul E. Capetz, Carlos F. Cardoza-Orlandi, Patrick W. Carey, Barbara Carvill, Hal Cauthron, Subhadra Mitra Channa, Mark D. Chapman, James H. Charlesworth, Kenneth R. Chase, Chen Zemin, Luciano Chianeque, Philip Chia Phin Yin, Francisca H. Chimhanda, Daniel Chiquete, John T. Chirban, Soobin Choi, Robert Choquette, Mita Choudhury, Gerald Christianson, John Chryssavgis, Sejong Chun, Esther Chung-Kim, Charles M. A. Clark, Elizabeth A. Clark, Sathianathan Clarke, Fred Cloud, John B. Cobb, W. Owen Cole, John A Coleman, John J. Collins, Sylvia Collins-Mayo, Paul K. Conkin, Beth A. Conklin, Sean Connolly, Demetrios J. Constantelos, Michael A. Conway, Paula M. Cooey, Austin Cooper, Michael L. Cooper-White, Pamela Cooper-White, L. William Countryman, Sérgio Coutinho, Pamela Couture, Shannon Craigo-Snell, James L. Crenshaw, David Crowner, Humberto Horacio Cucchetti, Lawrence S. Cunningham, Elizabeth Mason Currier, Emmanuel Cutrone, Mary L. Daniel, David D. Daniels, Robert Darden, Rolf Darge, Isaiah Dau, Jeffry C. Davis, Jane Dawson, Valentin Dedji, John W. de Gruchy, Paul DeHart, Wendy J. Deichmann Edwards, Miguel A. De La Torre, George E. Demacopoulos, Thomas de Mayo, Leah DeVun, Beatriz de Vasconcellos Dias, Dennis C. Dickerson, John M. Dillon, Luis Miguel Donatello, Igor Dorfmann-Lazarev, Susanna Drake, Jonathan A. Draper, N. Dreher Martin, Otto Dreydoppel, Angelyn Dries, A. J. Droge, Francis X. D'Sa, Marilyn Dunn, Nicole Wilkinson Duran, Rifaat Ebied, Mark J. Edwards, William H. Edwards, Leonard H. Ehrlich, Nancy L. Eiesland, Martin Elbel, J. Harold Ellens, Stephen Ellingson, Marvin M. Ellison, Robert Ellsberg, Jean Bethke Elshtain, Eldon Jay Epp, Peter C. Erb, Tassilo Erhardt, Maria Erling, Noel Leo Erskine, Gillian R. Evans, Virginia Fabella, Michael A. Fahey, Edward Farley, Margaret A. Farley, Wendy Farley, Robert Fastiggi, Seena Fazel, Duncan S. Ferguson, Helwar Figueroa, Paul Corby Finney, Kyriaki Karidoyanes FitzGerald, Thomas E. FitzGerald, John R. Fitzmier, Marie Therese Flanagan, Sabina Flanagan, Claude Flipo, Ronald B. Flowers, Carole Fontaine, David Ford, Mary Ford, Stephanie A. Ford, Jim Forest, William Franke, Robert M. Franklin, Ruth Franzén, Edward H. Friedman, Samuel Frouisou, Lorelei F. Fuchs, Jojo M. Fung, Inger Furseth, Richard R. Gaillardetz, Brandon Gallaher, China Galland, Mark Galli, Ismael García, Tharscisse Gatwa, Jean-Marie Gaudeul, Luis María Gavilanes del Castillo, Pavel L. Gavrilyuk, Volney P. Gay, Metropolitan Athanasios Geevargis, Kondothra M. George, Mary Gerhart, Simon Gikandi, Maurice Gilbert, Michael J. Gillgannon, Verónica Giménez Beliveau, Terryl Givens, Beth Glazier-McDonald, Philip Gleason, Menghun Goh, Brian Golding, Bishop Hilario M. Gomez, Michelle A. Gonzalez, Donald K. Gorrell, Roy Gottfried, Tamara Grdzelidze, Joel B. Green, Niels Henrik Gregersen, Cristina Grenholm, Herbert Griffiths, Eric W. Gritsch, Erich S. Gruen, Christoffer H. Grundmann, Paul H. Gundani, Jon P. Gunnemann, Petre Guran, Vidar L. Haanes, Jeremiah M. Hackett, Getatchew Haile, Douglas John Hall, Nicholas Hammond, Daphne Hampson, Jehu J. Hanciles, Barry Hankins, Jennifer Haraguchi, Stanley S. Harakas, Anthony John Harding, Conrad L. Harkins, J. William Harmless, Marjory Harper, Amir Harrak, Joel F. Harrington, Mark W. Harris, Susan Ashbrook Harvey, Van A. Harvey, R. Chris Hassel, Jione Havea, Daniel Hawk, Diana L. Hayes, Leslie Hayes, Priscilla Hayner, S. Mark Heim, Simo Heininen, Richard P. Heitzenrater, Eila Helander, David Hempton, Scott H. Hendrix, Jan-Olav Henriksen, Gina Hens-Piazza, Carter Heyward, Nicholas J. Higham, David Hilliard, Norman A. Hjelm, Peter C. Hodgson, Arthur Holder, M. Jan Holton, Dwight N. Hopkins, Ronnie Po-chia Hsia, Po-Ho Huang, James Hudnut-Beumler, Jennifer S. Hughes, Leonard M. Hummel, Mary E. Hunt, Laennec Hurbon, Mark Hutchinson, Susan E. Hylen, Mary Beth Ingham, H. Larry Ingle, Dale T. Irvin, Jon Isaak, Paul John Isaak, Ada María Isasi-Díaz, Hans Raun Iversen, Margaret C. Jacob, Arthur James, Maria Jansdotter-Samuelsson, David Jasper, Werner G. Jeanrond, Renée Jeffery, David Lyle Jeffrey, Theodore W. Jennings, David H. Jensen, Robin Margaret Jensen, David Jobling, Dale A. Johnson, Elizabeth A. Johnson, Maxwell E. Johnson, Sarah Johnson, Mark D. Johnston, F. Stanley Jones, James William Jones, John R. Jones, Alissa Jones Nelson, Inge Jonsson, Jan Joosten, Elizabeth Judd, Mulambya Peggy Kabonde, Robert Kaggwa, Sylvester Kahakwa, Isaac Kalimi, Ogbu U. Kalu, Eunice Kamaara, Wayne C. Kannaday, Musimbi Kanyoro, Veli-Matti Kärkkäinen, Frank Kaufmann, Léon Nguapitshi Kayongo, Richard Kearney, Alice A. Keefe, Ralph Keen, Catherine Keller, Anthony J. Kelly, Karen Kennelly, Kathi Lynn Kern, Fergus Kerr, Edward Kessler, George Kilcourse, Heup Young Kim, Kim Sung-Hae, Kim Yong-Bock, Kim Yung Suk, Richard King, Thomas M. King, Robert M. Kingdon, Ross Kinsler, Hans G. Kippenberg, Cheryl A. Kirk-Duggan, Clifton Kirkpatrick, Leonid Kishkovsky, Nadieszda Kizenko, Jeffrey Klaiber, Hans-Josef Klauck, Sidney Knight, Samuel Kobia, Robert Kolb, Karla Ann Koll, Heikki Kotila, Donald Kraybill, Philip D. W. Krey, Yves Krumenacker, Jeffrey Kah-Jin Kuan, Simanga R. Kumalo, Peter Kuzmic, Simon Shui-Man Kwan, Kwok Pui-lan, André LaCocque, Stephen E. Lahey, John Tsz Pang Lai, Emiel Lamberts, Armando Lampe, Craig Lampe, Beverly J. Lanzetta, Eve LaPlante, Lizette Larson-Miller, Ariel Bybee Laughton, Leonard Lawlor, Bentley Layton, Robin A. Leaver, Karen Lebacqz, Archie Chi Chung Lee, Marilyn J. Legge, Hervé LeGrand, D. L. LeMahieu, Raymond Lemieux, Bill J. Leonard, Ellen M. Leonard, Outi Leppä, Jean Lesaulnier, Nantawan Boonprasat Lewis, Henrietta Leyser, Alexei Lidov, Bernard Lightman, Paul Chang-Ha Lim, Carter Lindberg, Mark R. Lindsay, James R. Linville, James C. Livingston, Ann Loades, David Loades, Jean-Claude Loba-Mkole, Lo Lung Kwong, Wati Longchar, Eleazar López, David W. Lotz, Andrew Louth, Robin W. Lovin, William Luis, Frank D. Macchia, Diarmaid N. J. MacCulloch, Kirk R. MacGregor, Marjory A. MacLean, Donald MacLeod, Tomas S. Maddela, Inge Mager, Laurenti Magesa, David G. Maillu, Fortunato Mallimaci, Philip Mamalakis, Kä Mana, Ukachukwu Chris Manus, Herbert Robinson Marbury, Reuel Norman Marigza, Jacqueline Mariña, Antti Marjanen, Luiz C. L. Marques, Madipoane Masenya (ngwan'a Mphahlele), Caleb J. D. Maskell, Steve Mason, Thomas Massaro, Fernando Matamoros Ponce, András Máté-Tóth, Odair Pedroso Mateus, Dinis Matsolo, Fumitaka Matsuoka, John D'Arcy May, Yelena Mazour-Matusevich, Theodore Mbazumutima, John S. McClure, Christian McConnell, Lee Martin McDonald, Gary B. McGee, Thomas McGowan, Alister E. McGrath, Richard J. McGregor, John A. McGuckin, Maud Burnett McInerney, Elsie Anne McKee, Mary B. McKinley, James F. McMillan, Ernan McMullin, Kathleen E. McVey, M. 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Nicholson, George W. E. Nickelsburg, Tatyana Nikolskaya, Damayanthi M. A. Niles, Bertil Nilsson, Nyambura Njoroge, Fidelis Nkomazana, Mary Beth Norton, Christian Nottmeier, Sonene Nyawo, Anthère Nzabatsinda, Edward T. Oakes, Gerald O'Collins, Daniel O'Connell, David W. Odell-Scott, Mercy Amba Oduyoye, Kathleen O'Grady, Oyeronke Olajubu, Thomas O'Loughlin, Dennis T. Olson, J. Steven O'Malley, Cephas N. Omenyo, Muriel Orevillo-Montenegro, César Augusto Ornellas Ramos, Agbonkhianmeghe E. Orobator, Kenan B. Osborne, Carolyn Osiek, Javier Otaola Montagne, Douglas F. Ottati, Anna May Say Pa, Irina Paert, Jerry G. Pankhurst, Aristotle Papanikolaou, Samuele F. Pardini, Stefano Parenti, Peter Paris, Sung Bae Park, Cristián G. Parker, Raquel Pastor, Joseph Pathrapankal, Daniel Patte, W. Brown Patterson, Clive Pearson, Keith F. Pecklers, Nancy Cardoso Pereira, David Horace Perkins, Pheme Perkins, Edward N. Peters, Rebecca Todd Peters, Bishop Yeznik Petrossian, Raymond Pfister, Peter C. Phan, Isabel Apawo Phiri, William S. F. Pickering, Derrick G. Pitard, William Elvis Plata, Zlatko Plese, John Plummer, James Newton Poling, Ronald Popivchak, Andrew Porter, Ute Possekel, James M. Powell, Enos Das Pradhan, Devadasan Premnath, Jaime Adrían Prieto Valladares, Anne Primavesi, Randall Prior, María Alicia Puente Lutteroth, Eduardo Guzmão Quadros, Albert Rabil, Laurent William Ramambason, Apolonio M. Ranche, Vololona Randriamanantena Andriamitandrina, Lawrence R. Rast, Paul L. Redditt, Adele Reinhartz, Rolf Rendtorff, Pål Repstad, James N. Rhodes, John K. Riches, Joerg Rieger, Sharon H. Ringe, Sandra Rios, Tyler Roberts, David M. Robinson, James M. Robinson, Joanne Maguire Robinson, Richard A. H. Robinson, Roy R. Robson, Jack B. Rogers, Maria Roginska, Sidney Rooy, Rev. Garnett Roper, Maria José Fontelas Rosado-Nunes, Andrew C. Ross, Stefan Rossbach, François Rossier, John D. Roth, John K. Roth, Phillip Rothwell, Richard E. 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Yee, Viktor Yelensky, Yeo Khiok-Khng, Gustav K. K. Yeung, Angela Yiu, Amos Yong, Yong Ting Jin, You Bin, Youhanna Nessim Youssef, Eliana Yunes, Robert Michael Zaller, Valarie H. Ziegler, Barbara Brown Zikmund, Joyce Ann Zimmerman, Aurora Zlotnik, Zhuo Xinping
- Edited by Daniel Patte, Vanderbilt University, Tennessee
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- The Cambridge Dictionary of Christianity
- Published online:
- 05 August 2012
- Print publication:
- 20 September 2010, pp xi-xliv
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EXECUTIVE COMMITTEE WORKING GROUP YOUNG ASTRONOMERS EVENTS
- Michèle Gerbaldi, Jean-Pierre De Greve, Michal Dovčiak, Oddbjørn Engvold, Edward F. Guinan, John B. Hearnshaw, Melanie Johnston-Hollitt, Jay M. Pasachoff, John R. Percy, Ignasi Ribas, James C. White, Michal Dovčiak, René Goosmann, Tomáš Pecháček, Ivana Stoklasová
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- Journal:
- Proceedings of the International Astronomical Union / Volume 3 / Issue T26B / December 2007
- Published online by Cambridge University Press:
- 18 November 2008, pp. 242-247
- Print publication:
- December 2007
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At the IAU XXV General Assembly in Sydney, 2003, a questionnaire on the perception of participation of “young astronomers” at IAU meeting was distributed. Following the conclusions from the analysis of this questionnaire, the IAU EC recommended in 2004 that the “young astronomers” concept at the next GA in Prague should be worked out with specific activities.
Animal Health – The Scientist
- D.S. Edwards, A.M. Johnston
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- Journal:
- Proceedings of the British Society of Animal Science / Volume 2001 / 2001
- Published online by Cambridge University Press:
- 20 November 2017, pp. 272-273
- Print publication:
- 2001
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Food animal health impacts on productivity, animal welfare and human health. What happens to an animal on the farm and its resulting health status has an important influence on the quality, safety and wholesomeness of the meat and offal obtained from that animal. Our research has largely been focused on the environmental influences on beef cattle and sheep health, the farm environment and management, in particular and how it impacts on veterinary public health, i.e. food safety, and animal welfare. The main objective of the study was to examine the use of information about the health and management of cattle and lambs on the farm to predict the risk of visible lesions at slaughter. Th e feasibility of identifying farm-level risk factors for gross lesions detectable during post-mortem meat inspection has been investigated, from which the findings of the sheep study have been published (Edwards, et al. 1999).
Single Nucleotide Primer Extension (SNuPE) analysis of the G6PD gene in somatic cells and oocytes of a kangaroo (Macropus robustus)
- DEBBIE WATSON, ANITA S. JACOMBS, DAVID A. LOEBEL, EDWARD S. ROBINSON, PETER G. JOHNSTON
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- Journal:
- Genetical Research / Volume 75 / Issue 3 / June 2000
- Published online by Cambridge University Press:
- 01 June 2000, pp. 269-274
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cDNA sequence analysis of the X-linked glucose-6-phosphate dehydrogenase (G6PD) gene has shown a base difference between two subspecies of the kangaroo, Macropus robustus robustus (wallaroo) and M. r. erubescens (euro). A thymine residue in the wallaroo at position 358 in exon 5 has been replaced by a cytosine residue in the euro, which accounts for the previously reported electrophoretic difference between the two subspecies. This base difference allowed use of the Single Nucleotide Primer Extension (SNuPE) technique to study allele-specific expression of G6PD at the transcriptional level. We began by examining G6PD expression in somatic cells and observed complete paternal X inactivation in all somatic tissues of adult female heterozygotes, whereas we found partial paternal allele activity in cultured fibroblasts, thus confirming previous allozyme electrophoresis studies. In late dictyate oocytes from an adult heterozygote, the assay also detected expression of both the maternal and paternal alleles at the G6PD locus, with the maternal allele showing preferential expression. Thus reactivation of the inactive paternally derived X chromosome occurs during oogenesis in M. robustus, although the exact timing of reactivation remains to be determined.